Polynucleotides Undereye

Undereye polynucleotides are an advanced regenerative treatment specifically designed for the highly delicate tear trough region. Utilizing highly purified DNA fractions, this bio-stimulating injectable works at a cellular level to repair and rejuvenate the thin skin beneath the eyes.

Unlike traditional hyaluronic acid tear trough fillers that simply mask hollowness by adding physical volume, polynucleotides actively regenerate the tissue itself. Once introduced to the area, they stimulate your body’s fibroblasts to produce fresh collagen and elastin. This naturally thickens the fragile undereye skin, improves microcirculation, and deeply hydrates the area without the risk of water retention or the blueish tint sometimes associated with standard fillers.

  • Cellular Repair: Naturally regenerates and thickens the thin, fragile skin beneath the eyes for improved structural support.
  • Brightens Dark Circles: Enhances local microcirculation and reduces vascular pooling to visibly fade dark undereye shadowing.
  • Smooths Crepiness: Stimulates collagen and elastin production to soften fine lines and crepey skin texture.
  • Zero Puffiness: Unlike traditional tear trough fillers, polynucleotides do not draw in excess water, eliminating the risk of long-term undereye puffiness.

To ensure a safe and effective procedure, please arrive at the clinic completely makeup-free with a clean face.

Upon your arrival, your clinician will thoroughly cleanse the delicate skin around your eyes. Depending on your comfort level, we may apply a topical anesthetic cream prior to the procedure to minimize any mild discomfort.

Once the skin is fully prepared, the polynucleotide gel is carefully injected into the targeted undereye area. Your clinician will typically use a micro-cannula or an ultra-fine needle for this procedure to ensure absolute precision and minimize the risk of bruising in this highly vascular region.

Immediately after the treatment, it is completely normal to experience small raised bumps, mild redness, or swelling under the eyes. Because the undereye tissue is so delicate, minor bruising may also occur. These localized reactions are expected and typically resolve within 24 to 48 hours.

  • The First 24 Hours: Please do not touch, rub, or apply any pressure to your eyes. You must completely avoid applying makeup, concealers, or active eye creams to the treated area to prevent infection.
  • Heat & Exertion: Avoid intensive cardiovascular exercise, saunas, steam rooms, and hot showers for 24 hours following your appointment to help minimize swelling.
  • Sun Protection: Wear sunglasses outdoors to protect the sensitive, healing skin from UV exposure.

Because this treatment actively stimulates your body to rebuild its own cells, the visual improvements are gradual and highly natural. Maximal and optimum results will become visible 3 to 4 weeks after your final session in the recommended treatment course, as the newly formed collagen networks fully mature and stabilize.

I am a heading
Procedure time
45 min
Results timeframe
3-4 weeks
Estimated downtime
24 hours
From
£120
Book now

Polynucleotides Undereye

A targeted regenerative injectable that uses purified DNA fractions to repair delicate tissue, brighten dark circles, and smooth the undereye area.
Procedure time
45 min
Results timeframe
3-4 weeks
Estimated downtime
24 hours
From
£120
Book now

Undereye polynucleotides are an advanced regenerative treatment specifically designed for the highly delicate tear trough region. Utilizing highly purified DNA fractions, this bio-stimulating injectable works at a cellular level to repair and rejuvenate the thin skin beneath the eyes.

Unlike traditional hyaluronic acid tear trough fillers that simply mask hollowness by adding physical volume, polynucleotides actively regenerate the tissue itself. Once introduced to the area, they stimulate your body’s fibroblasts to produce fresh collagen and elastin. This naturally thickens the fragile undereye skin, improves microcirculation, and deeply hydrates the area without the risk of water retention or the blueish tint sometimes associated with standard fillers.

  • Cellular Repair: Naturally regenerates and thickens the thin, fragile skin beneath the eyes for improved structural support.
  • Brightens Dark Circles: Enhances local microcirculation and reduces vascular pooling to visibly fade dark undereye shadowing.
  • Smooths Crepiness: Stimulates collagen and elastin production to soften fine lines and crepey skin texture.
  • Zero Puffiness: Unlike traditional tear trough fillers, polynucleotides do not draw in excess water, eliminating the risk of long-term undereye puffiness.

To ensure a safe and effective procedure, please arrive at the clinic completely makeup-free with a clean face.

Upon your arrival, your clinician will thoroughly cleanse the delicate skin around your eyes. Depending on your comfort level, we may apply a topical anesthetic cream prior to the procedure to minimize any mild discomfort.

Once the skin is fully prepared, the polynucleotide gel is carefully injected into the targeted undereye area. Your clinician will typically use a micro-cannula or an ultra-fine needle for this procedure to ensure absolute precision and minimize the risk of bruising in this highly vascular region.

Immediately after the treatment, it is completely normal to experience small raised bumps, mild redness, or swelling under the eyes. Because the undereye tissue is so delicate, minor bruising may also occur. These localized reactions are expected and typically resolve within 24 to 48 hours.

  • The First 24 Hours: Please do not touch, rub, or apply any pressure to your eyes. You must completely avoid applying makeup, concealers, or active eye creams to the treated area to prevent infection.
  • Heat & Exertion: Avoid intensive cardiovascular exercise, saunas, steam rooms, and hot showers for 24 hours following your appointment to help minimize swelling.
  • Sun Protection: Wear sunglasses outdoors to protect the sensitive, healing skin from UV exposure.

Because this treatment actively stimulates your body to rebuild its own cells, the visual improvements are gradual and highly natural. Maximal and optimum results will become visible 3 to 4 weeks after your final session in the recommended treatment course, as the newly formed collagen networks fully mature and stabilize.

Treatment Outcomes

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Frequently Asked Questions

Reviews

Absolutely amazing experience. I was super nervous with it being my first time having an injectable treatment but Dr Hussain put me at ease from the very beginning, answering all my questions and explaining the entire process throughly. I couldn’t recommend them enough! Zorah Clinic has truly become my go to for all aesthetic treatments!
Hannah
I had a facial by Hajrah, initially I was very reluctant as i am scared of needles however she explained the whole procedure so simply and put my mind at ease. The results I’ve seen from the facials have been amazing, definitely now my favourite treatment to get. Highly recommend!!
Amarah
Absolutely amazing experience. I was super nervous with it being my first time having an injectable treatment but Dr Hussain put me at ease from the very beginning, answering all my questions and explaining the entire process throughly. I couldn’t recommend them enough! Zorah Clinic has truly become my go to for all aesthetic treatments!
Emily
Friendly staff, really helpful, advised me on a lot more than what I was there for
A
5.0
Based on 31 reviews
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Meet Our Team

Dr Z Hussain

MBBS
Medical Director
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Hajrah

Pharmacist Prescriber, Dermatology
Clinical Director
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