Polynucleotides Undereye
Undereye polynucleotides are an advanced regenerative treatment specifically designed for the highly delicate tear trough region. Utilizing highly purified DNA fractions, this bio-stimulating injectable works at a cellular level to repair and rejuvenate the thin skin beneath the eyes.
Unlike traditional hyaluronic acid tear trough fillers that simply mask hollowness by adding physical volume, polynucleotides actively regenerate the tissue itself. Once introduced to the area, they stimulate your body’s fibroblasts to produce fresh collagen and elastin. This naturally thickens the fragile undereye skin, improves microcirculation, and deeply hydrates the area without the risk of water retention or the blueish tint sometimes associated with standard fillers.
- Cellular Repair: Naturally regenerates and thickens the thin, fragile skin beneath the eyes for improved structural support.
- Brightens Dark Circles: Enhances local microcirculation and reduces vascular pooling to visibly fade dark undereye shadowing.
- Smooths Crepiness: Stimulates collagen and elastin production to soften fine lines and crepey skin texture.
- Zero Puffiness: Unlike traditional tear trough fillers, polynucleotides do not draw in excess water, eliminating the risk of long-term undereye puffiness.
To ensure a safe and effective procedure, please arrive at the clinic completely makeup-free with a clean face.
Upon your arrival, your clinician will thoroughly cleanse the delicate skin around your eyes. Depending on your comfort level, we may apply a topical anesthetic cream prior to the procedure to minimize any mild discomfort.
Once the skin is fully prepared, the polynucleotide gel is carefully injected into the targeted undereye area. Your clinician will typically use a micro-cannula or an ultra-fine needle for this procedure to ensure absolute precision and minimize the risk of bruising in this highly vascular region.
Immediately after the treatment, it is completely normal to experience small raised bumps, mild redness, or swelling under the eyes. Because the undereye tissue is so delicate, minor bruising may also occur. These localized reactions are expected and typically resolve within 24 to 48 hours.
- The First 24 Hours: Please do not touch, rub, or apply any pressure to your eyes. You must completely avoid applying makeup, concealers, or active eye creams to the treated area to prevent infection.
- Heat & Exertion: Avoid intensive cardiovascular exercise, saunas, steam rooms, and hot showers for 24 hours following your appointment to help minimize swelling.
- Sun Protection: Wear sunglasses outdoors to protect the sensitive, healing skin from UV exposure.
Because this treatment actively stimulates your body to rebuild its own cells, the visual improvements are gradual and highly natural. Maximal and optimum results will become visible 3 to 4 weeks after your final session in the recommended treatment course, as the newly formed collagen networks fully mature and stabilize.
Our Elite Polynucleotide option uses Rejuran, one of the most recognised premium polynucleotide treatments in Korean aesthetic medicine.
Like our Signature tier, Rejuran works by supporting the skin’s natural repair processes rather than adding volume or changing facial structure. It is designed to improve overall skin quality, helping with concerns such as fine lines, crepey texture, reduced elasticity, dullness and tired-looking skin.
Where Rejuran stands apart is in its reputation as a highly refined, premium regenerative skin treatment. It is particularly well suited to patients who want a more advanced skin-quality treatment, especially in delicate areas such as the under-eyes, or for those wanting a more elevated approach to collagen support, repair and long-term skin resilience.
Our Signature Plinest tier remains an excellent medical-grade polynucleotide option and is suitable for many patients starting their regenerative skin journey. Our Elite Rejuran tier is for those who want to take this a step further with a premium Korean polynucleotide treatment, chosen for its strong reputation in skin healing, texture refinement and natural-looking rejuvenation.
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Polynucleotides Undereye
Undereye polynucleotides are an advanced regenerative treatment specifically designed for the highly delicate tear trough region. Utilizing highly purified DNA fractions, this bio-stimulating injectable works at a cellular level to repair and rejuvenate the thin skin beneath the eyes.
Unlike traditional hyaluronic acid tear trough fillers that simply mask hollowness by adding physical volume, polynucleotides actively regenerate the tissue itself. Once introduced to the area, they stimulate your body’s fibroblasts to produce fresh collagen and elastin. This naturally thickens the fragile undereye skin, improves microcirculation, and deeply hydrates the area without the risk of water retention or the blueish tint sometimes associated with standard fillers.
- Cellular Repair: Naturally regenerates and thickens the thin, fragile skin beneath the eyes for improved structural support.
- Brightens Dark Circles: Enhances local microcirculation and reduces vascular pooling to visibly fade dark undereye shadowing.
- Smooths Crepiness: Stimulates collagen and elastin production to soften fine lines and crepey skin texture.
- Zero Puffiness: Unlike traditional tear trough fillers, polynucleotides do not draw in excess water, eliminating the risk of long-term undereye puffiness.
To ensure a safe and effective procedure, please arrive at the clinic completely makeup-free with a clean face.
Upon your arrival, your clinician will thoroughly cleanse the delicate skin around your eyes. Depending on your comfort level, we may apply a topical anesthetic cream prior to the procedure to minimize any mild discomfort.
Once the skin is fully prepared, the polynucleotide gel is carefully injected into the targeted undereye area. Your clinician will typically use a micro-cannula or an ultra-fine needle for this procedure to ensure absolute precision and minimize the risk of bruising in this highly vascular region.
Immediately after the treatment, it is completely normal to experience small raised bumps, mild redness, or swelling under the eyes. Because the undereye tissue is so delicate, minor bruising may also occur. These localized reactions are expected and typically resolve within 24 to 48 hours.
- The First 24 Hours: Please do not touch, rub, or apply any pressure to your eyes. You must completely avoid applying makeup, concealers, or active eye creams to the treated area to prevent infection.
- Heat & Exertion: Avoid intensive cardiovascular exercise, saunas, steam rooms, and hot showers for 24 hours following your appointment to help minimize swelling.
- Sun Protection: Wear sunglasses outdoors to protect the sensitive, healing skin from UV exposure.
Because this treatment actively stimulates your body to rebuild its own cells, the visual improvements are gradual and highly natural. Maximal and optimum results will become visible 3 to 4 weeks after your final session in the recommended treatment course, as the newly formed collagen networks fully mature and stabilize.
Our Elite Polynucleotide option uses Rejuran, one of the most recognised premium polynucleotide treatments in Korean aesthetic medicine.
Like our Signature tier, Rejuran works by supporting the skin’s natural repair processes rather than adding volume or changing facial structure. It is designed to improve overall skin quality, helping with concerns such as fine lines, crepey texture, reduced elasticity, dullness and tired-looking skin.
Where Rejuran stands apart is in its reputation as a highly refined, premium regenerative skin treatment. It is particularly well suited to patients who want a more advanced skin-quality treatment, especially in delicate areas such as the under-eyes, or for those wanting a more elevated approach to collagen support, repair and long-term skin resilience.
Our Signature Plinest tier remains an excellent medical-grade polynucleotide option and is suitable for many patients starting their regenerative skin journey. Our Elite Rejuran tier is for those who want to take this a step further with a premium Korean polynucleotide treatment, chosen for its strong reputation in skin healing, texture refinement and natural-looking rejuvenation.
Frequently Asked Questions
How long do the results of undereye polynucleotides last?
Once your initial treatment course is complete, results in the tear trough area typically last between 6 to 9 months. Because polynucleotides actively regenerate and thicken the delicate skin rather than just temporarily masking hollows, the cellular improvements are long-lasting. To maintain a bright, refreshed undereye, we recommend a single maintenance session every 6 months.
Does the undereye polynucleotide treatment hurt?
While the skin beneath the eyes is exceptionally delicate, the procedure is highly tolerable. We use ultra-fine needles and your clinician may apply a premium topical anesthetic cream beforehand to ensure your comfort. You may feel a slight pressure as the product is placed, but the process is gentle, fast, and meticulously controlled.
What is the difference between undereye polynucleotides and tear trough filler?
Traditional tear trough fillers use hyaluronic acid to physically plump and fill hollows. However, hyaluronic acid naturally draws in water, which can sometimes lead to chronic puffiness or a blueish tint under the skin in this fragile area. Polynucleotides do not add artificial volume or attract excess water. Instead, they regenerate your own cells, naturally thickening the skin and improving microcirculation to fade dark circles without the risk of long-term puffiness.
Will my eyes be very puffy or bruised after the treatment?
It is completely normal to experience small, raised bumps, mild swelling and redness directly under the eyes immediately following your procedure. Because the tear trough is a highly vascular area, minor bruising is also a common and expected reaction. The initial bumps and swelling typically subside within 24 to 48 hours, while any bruising will naturally fade over the following days.
How many sessions will I need to see a difference in my dark circles?
Because this is a biological treatment that requires your cells to rebuild themselves, a single session is not enough to achieve clinical results. To successfully thicken the delicate tissue and significantly brighten dark circles, we recommend a targeted course of four sessions, spaced three to four weeks apart. This allows the regenerative signaling to effectively establish new, strong collagen networks.
What is the difference between your Signature and Elite polynucleotide treatments?
Our Elite Polynucleotide option uses Rejuran, one of the most recognised premium polynucleotide treatments in Korean aesthetic medicine.
Like our Signature tier, Rejuran works by supporting the skin’s natural repair processes rather than adding volume or changing facial structure. It is designed to improve overall skin quality, helping with concerns such as fine lines, crepey texture, reduced elasticity, dullness and tired-looking skin.
Where Rejuran stands apart is in its reputation as a highly refined, premium regenerative skin treatment. It is particularly well suited to patients who want a more advanced skin-quality treatment, especially in delicate areas such as the under-eyes, or for those wanting a more elevated approach to collagen support, repair and long-term skin resilience.
Our Signature Plinest tier remains an excellent medical-grade polynucleotide option and is suitable for many patients starting their regenerative skin journey. Our Elite Rejuran tier is for those who want to take this a step further with a premium Korean polynucleotide treatment, chosen for its strong reputation in skin healing, texture refinement and natural-looking rejuvenation.
